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Spironolactone 1%, Minoxidil 5% Melatonin 2% and Tretinoin 0.01% Topical Scalp Serum (Alcohol Free)

Spironolactone 1%, Minoxidil 5% Melatonin 2% and Tretinoin 0.01% Topical Scalp Serum (Alcohol Free)

The active ingredients in this formulation include Spironolactone 1%, Minoxidil 5% Melatonin 2% and Tretinoin 0.01% Topical Scalp Serum (Alcohol Free). Spironolactone acts as an anti-androgen, reducing the effects of hormones that can contribute to hair thinning. Minoxidil is a potent vasodilator utilised in the treatment of hair loss and pattern baldness. It functions by enhancing blood circulation to the scalp, thereby stimulating hair growth. Tretinoin, a retinoid, enhances the penetration of minoxidil and may improve the health and function of the hair follicle. Melatonin is included for its anti-inflammatory, DHT blocking and antioxidant effects, which can help repair and rejuvenate the skin. Making this formulation an effective treatment for conditions such as Alopecia, Androgenic Alopecia and Female Pattern Hair Loss.

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Personalised Hair Growth Treatments

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Formula Information

GrowBack's Spironolactone 1%, Minoxidil 5%, Melatonin 2% and Tretinoin 0.01% Topical Scalp Serum (Alcohol Free) Scalp Serum is a specially compounded liquid formulation designed for topical application to the scalp. This unique blend of active ingredients is dispensed in a dropper bottle for precise and controlled administration, ensuring targeted treatment for a variety of hair loss and scalp conditions. Spironolactone is a medication that has anti-androgenic properties. It works by inhibiting the action of androgens (male hormones) at the receptor sites in the hair follicles. Androgens can contribute to hair loss in women with conditions like polycystic ovary syndrome (PCOS) and are also implicated in other skin conditions such as acne and hirsutism. By blocking these hormones, spironolactone can help to prevent hair loss and improve skin conditions that are exacerbated by excess androgen levels. Stops hair loss and regrows hair by blocking DHT from attaching to its receptors. Minoxidil, a potent vasodilator, works by increasing blood flow to the scalp, thereby stimulating hair growth. Minoxidil may stimulate the growth of human hairs by prolonging anagen through these proliferative and anti-apoptotic effects on dermal papillary cells (DPCs). Minoxidil, the second active ingredient, is a well-known vasodilator that has been proven to stimulate hair growth and slow balding. It functions by widening blood vessels and opening potassium channels, which allows more oxygen, blood, and nutrients to the follicle. This results in a revitalisation of shrunken hair follicles, increasing their size, and prolonging the growth phase of the hair cycle. Tretinoin, a derivative of vitamin A, is included at a 0.01% concentration. It promotes skin cell turnover and can help improve the skin's texture and tone. In the context of hair loss, tretinoin is believed to enhance the penetration of minoxidil, increasing its effectiveness. Supercharges Minoxidil to promote denser hair regrowth. Melatonin, a powerful antioxidant, protects the scalp from oxidative damage that can lead to hair loss, aids in reducing inflammation, blocks dihydrotestosterone (DHT) and aids in promoting healthy skin cells on the scalp. This powerful combination formulation is an effective treatment for a range of hair loss and scalp conditions, including male and female pattern baldness, alopecia areata, and preventative hair loss. When used as directed, this formulation is safe and effective. It is important for patients to adhere to our prescribers instructions for use and not to exceed the recommended dosage. Potential side effects may include scalp irritation, dryness, and itching. It is recommended to consult with a healthcare professional if these or any other side effects occur. The carrier agent used to deliver the active ingredient to your scalp is free from the potentially harsh chemicals ethanol and propylene glycol. We opted for a highly spreadable hydrophilic solution containing mineral salts of vegetable origin (TrichoSol™). Making this an alcohol-free treatment. Base solution (TrichoSol™): Aqua, lactic Acid, polysorbate 80, lavandula officinalis water parfum phenoxyethanol, rosmarinus officinalis leaf oil, ethylhexylglycerin, BHT, juniperus communis fruit oil, juniperus virginiana wood oil, amyris balsamifera bark oil, lavandula angustifolia herb oil, melaleuca alternifolia leaf oil, eucalyptus globulus leaf oil. If you have any questions about GrowBack’s Spironolactone 1%, Minoxidil 5%, Melatonin 2% and Tretinoin 0.01% Topical Scalp Serum (Alcohol Free) , please do not hesitate to contact us. Our team is here to provide the information and support you need.

How Does It Work

Spironolactone is a pharmaceutical ingredient that aids in hair health and growth by acting as an androgen receptor antagonist and reducing the levels of androgens in the body. Androgens, such as dihydrotestosterone (DHT), can lead to hair follicle shrinkage and hair loss, especially in conditions like androgenetic alopecia. By blocking these hormones, spironolactone helps to prevent follicular miniaturisation and promotes the growth of stronger, healthier hair. Its effectiveness in both men and women has been demonstrated through clinical studies, making it a valuable treatment for those seeking to combat hair thinning and improve hair density. Minoxidil is a well-known vasodilator that is commonly used to treat hair loss. It works by widening blood vessels and opening potassium channels, which allows more oxygen, blood, and nutrients to reach the hair follicles. This action can stimulate hair growth and extend the growth phase of the hair cycle. Tretinoin, a derivative of vitamin A, is included at a 0.01% concentration. It promotes skin cell turnover and can help improve the skin's texture and tone. In the context of hair loss, tretinoin is believed to enhance the penetration of minoxidil, increasing its effectiveness. Melatonin, a powerful antioxidant, protects the scalp from oxidative damage that can lead to hair loss, aids in reducing inflammation, blocks dihydrotestosterone (DHT) and aids in promoting healthy skin cells on the scalp. When Will I See Results? It usually takes months or years for you to lose hair, so it can take several weeks to GrowBack. 80% of our patients see results within 3-4 months. In the rare instance, that the results are not as desirable as you want, we can increase the strength or add other active ingredients based on your hair health profile. The best results will come from continued use of your recommended treatments and are seen after 4-6 months. You will need to maintain the treatment for continual growth and reduced hair shedding.

Possible Side Effects

Like all medicines, your Personalised Scalp Application can cause side effects, although not everybody gets them.

How To Use

This formulation can be used by both men and women. Avoid if pregnant or breast feeding. If you are on any medication, please check with our clinical prescriber before using this formulation. Always perform a patch test before applying to the whole scalp. Apply a small amount of the scalp serum on your scalp and leave on for a few hours. Monitor and observe to check for any irritation, redness, itching or blistering. If there is of these reactions please contact us immediately. If no reactions have been observed then proceed to apply the scalp serum to the areas of treatment. On the first application only use half the dosage amount and leave overnight. If you haven't had any reactions then continue your treatment at full optimal dosing as instructed. To apply a solution medication, we recommend the following steps: 1. Part your hair down the middle of your head. Then, use a dropper to apply the medication along the part, from the front of your scalp to the back. Make sure you continuously, but gently squeeze out small amounts of the medication as you work your way along the part with the dropper. 2. Part your hair a second and third time to the right and left of your middle part, about 2 inches down. Continuously apply the medication along each part from the front of your scalp to the back. 3. Part your hair a fourth and fifth time just above your right and left ears. Continuously apply the medication along each part from the front of your scalp to the back.

Safety Information

Talk to your prescriber: • If you suffer from heart disease, including abnormal heart rhythms or rates, angina, or chest pains and / or circulation disorders. • If you are at all unsure whether your scalp is normal and healthy. • If you, or a close relative, are suffering or has suffered cancer. • If you have had any allergic reactions to any applications. • If you are pregnant, breast feeding or are planning a family. • If you are unsure of why you have been prescribed this formula. Take special care when using this product: • Keep the product away from your eyes and mouth. • Wash your hands straight after application. • Before first use, perform a patch test as explained in initial consultation. • Store product as per dispensing label instructions. • Use pipette to measure doses. One dose is equivalent to 1ml. • Do not exceed 2ml within 24 hours. Driving and using machinery Using this product is not known to affect your ability to drive or use machinery. Continued use of application • You may need to use this medicine daily for at least 4 months before you see new hair growth, this is because hair growth is a slow process. • Hair growth may be soft and downy at the start but should eventually become the same as normal hair. • Once the hair has begun to re-grow, you need to continue using this medicine daily for the growth to continue. • When you stop using the medicine, the hair that has re-grown may disappear after 3-4 months and the balding / hair loss process will continue. • If you have no improvement in your hair growth after one year of use, you should discontinue treatment. • Your prescribing pharmacist will guide you each month and will monitor your hair growth progress.
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