Prostaquinon 3%, 17-alpha Estradiol 0.025% & Minoxidil 7% Topical Scalp Serum (Alcohol Free) The active ingredients in this formulation include Prostaquinon 3%, 17-alpha Estradiol 0.025% & Minoxidil 7% Topical Scalp Serum (Alcohol Free). Prostaquinon exerts anti-inflammatory and anti-oxidant effects and counteracts miniaturisation of hair follicles. 17-alpha Estradiol inhibits the conversion of testosterone to the metabolite dihydrotestosterone (DHT) by suppressing 5AR activity. In addition, by inhibiting dehydrogenase, it reduces the conversion process of androstenedione to testosterone, resulting in a reduction in the synthesis of testosterone and DHT. Minoxidil is a potent vasodilator utilised in the treatment of hair loss and pattern baldness. It functions by enhancing blood circulation to the scalp, thereby stimulating hair growth. Making this formulation an effective treatment for conditions such as Alopecia, Androgenic Alopecia and Menopausal Female Pattern Hair Loss. Personalised Hair Growth Treatments Ongoing Clinical Guidance and Support Medical Consultation Required Request Prescription Formula Information GrowBack's Prostaquinon 3%, 17-alpha Estradiol 0.025% & Minoxidil 7% Topical Scalp Serum (Alcohol Free) Scalp Serum is a specially compounded liquid formulation designed for topical application to the scalp. This unique blend of active ingredients is dispensed in a dropper bottle for precise and controlled administration, ensuring targeted treatment for a variety of hair loss and scalp conditions. Prostaquinon® is a specialised raw material from Fagron that exerts significant anti-inflammatory and antioxidant effects, which are crucial in maintaining healthy hair follicles and promoting hair growth. By counteracting the miniaturisation of hair follicles, Prostaquinon® helps prevent the progression of hair thinning and loss. A key mechanism of its action is the inhibition of prostaglandin PGD2, a compound that recent studies have shown to be elevated in individuals with alopecia. PGD2 has been linked to the suppression of hair growth and the promotion of hair follicle regression. By inhibiting PGD2, Prostaquinon® not only helps to sustain the anagen (growth) phase of the hair cycle but also supports overall scalp health by reducing inflammation and oxidative stress. These combined effects make Prostaquinon® a valuable ingredient in formulations aimed at treating and preventing hair loss, offering a multifaceted approach to enhancing hair density and vitality. 17-alpha Estradiol inhibits the conversion of testosterone to the metabolite dihydrotestosterone (DHT) by suppressing 5AR activity. In addition, by inhibiting dehydrogenase, it reduces the conversion process of androstenedione to testosterone, resulting in a reduction in the synthesis of testosterone and DHT. Minoxidil, a potent vasodilator, works by increasing blood flow to the scalp, thereby stimulating hair growth. Minoxidil may stimulate the growth of human hairs by prolonging anagen through these proliferative and anti-apoptotic effects on dermal papillary cells (DPCs). Minoxidil, the second active ingredient, is a well-known vasodilator that has been proven to stimulate hair growth and slow balding. It functions by widening blood vessels and opening potassium channels, which allows more oxygen, blood, and nutrients to the follicle. This results in a revitalisation of shrunken hair follicles, increasing their size, and prolonging the growth phase of the hair cycle. This powerful combination formulation is an effective treatment for a range of hair loss and scalp conditions, including male and female pattern baldness, alopecia areata, and preventative hair loss. When used as directed, this formulation is safe and effective. It is important for patients to adhere to our prescribers instructions for use and not to exceed the recommended dosage. Potential side effects may include scalp irritation, dryness, and itching. It is recommended to consult with a healthcare professional if these or any other side effects occur. The carrier agent used to deliver the active ingredient to your scalp is free from the potentially harsh chemicals ethanol and propylene glycol. We opted for a highly spreadable hydrophilic solution containing mineral salts of vegetable origin (TrichoSol™). Making this an alcohol-free treatment. Base solution (TrichoSol™): Aqua, lactic Acid, polysorbate 80, lavandula officinalis water parfum phenoxyethanol, rosmarinus officinalis leaf oil, ethylhexylglycerin, BHT, juniperus communis fruit oil, juniperus virginiana wood oil, amyris balsamifera bark oil, lavandula angustifolia herb oil, melaleuca alternifolia leaf oil, eucalyptus globulus leaf oil. If you have any questions about GrowBack'sProstaquinon 3%, 17-alpha Estradiol 0.025% & Minoxidil 7% Topical Scalp Serum (Alcohol Free) Scalp Serum , please do not hesitate to contact us. Our team is here to provide the information and support you need. How Does It Work Prostaquinon exerts anti-inflammatory and anti-oxidant effects and counteracts miniaturisation of hair follicles. 17-alpha Estradiol inhibits the conversion of testosterone to the metabolite dihydrotestosterone (DHT) by suppressing 5AR activity. In addition, by inhibiting dehydrogenase, it reduces the conversion process of androstenedione to testosterone, resulting in a reduction in the synthesis of testosterone and DHT. Minoxidil is a well-known vasodilator that is commonly used to treat hair loss. It works by widening blood vessels and opening potassium channels, which allows more oxygen, blood, and nutrients to reach the hair follicles. This action can stimulate hair growth and extend the growth phase of the hair cycle. When Will I See Results? It usually takes months or years for you to lose hair, so it can take several weeks to GrowBack. 80% of our patients see results within 3-4 months. In the rare instance, that the results are not as desirable as you want, we can increase the strength or add other active ingredients based on your hair health profile. The best results will come from continued use of your recommended treatments and are seen after 4-6 months. You will need to maintain the treatment for continual growth and reduced hair shedding. Possible Side Effects Like all medicines, your Personalised Scalp Application can cause side effects, although not everybody gets them. Personalised Scalp Applications may cause the following side effects of unknown frequency (frequency cannot be estimated from the available data): • Skin irritation may occur. If this happens stop using the product. • Unwanted non-scalp hair has occasionally been reported. Always wash your hands thoroughly after application and if you accidentally apply the solution to parts of the body other than the scalp, rinse thoroughly with plenty of water. • Scalp irritation such as local redness, itchiness, dryness, flaky skin have all been reported. This may be due to propylene glycol in the product. This is usually only a temporary effect, but if it is persistent, you should stop using this product. • Temporary hair loss may occur during the first 2 – 6 weeks of use. This is likely to be because of a change within the growth cycle and it should stop within a couple of weeks. If this hair loss continues for longer than 2 weeks, stop using the product and talk to your prescribing pharmacist. • Change in hair colour and / or texture may occur. Please be aware that this treatment may take up to 4-6 months of regular use to show noticeable results. How To Use This formulation can be used by both men and women. Avoid if pregnant or breast feeding. If you are on any medication, please check with our clinical prescriber before using this formulation. Always perform a patch test before applying to the whole scalp. Apply a small amount of the scalp serum on your scalp and leave on for a few hours. Monitor and observe to check for any irritation, redness, itching or blistering. If there is of these reactions please contact us immediately. If no reactions have been observed then proceed to apply the scalp serum to the areas of treatment. On the first application only use half the dosage amount and leave overnight. If you haven't had any reactions then continue your treatment at full optimal dosing as instructed. To apply a solution medication, we recommend the following steps: 1. Part your hair down the middle of your head. Then, use a dropper to apply the medication along the part, from the front of your scalp to the back. Make sure you continuously, but gently squeeze out small amounts of the medication as you work your way along the part with the dropper. 2. Part your hair a second and third time to the right and left of your middle part, about 2 inches down. Continuously apply the medication along each part from the front of your scalp to the back. 3. Part your hair a fourth and fifth time just above your right and left ears. Continuously apply the medication along each part from the front of your scalp to the back. Safety Information Talk to your prescriber: • If you suffer from heart disease, including abnormal heart rhythms or rates, angina, or chest pains and / or circulation disorders. • If you are at all unsure whether your scalp is normal and healthy. • If you, or a close relative, are suffering or has suffered cancer. • If you have had any allergic reactions to any applications. • If you are pregnant, breast feeding or are planning a family. • If you are unsure of why you have been prescribed this formula. Take special care when using this product: • Keep the product away from your eyes and mouth. • Wash your hands straight after application. • Before first use, perform a patch test as explained in initial consultation. • Store product as per dispensing label instructions. • Use pipette to measure doses. One dose is equivalent to 1ml. • Do not exceed 2ml within 24 hours. Side Effects – 17-alpha Estradiol - Generally the side effects are mild and localised at application site. These side effects below are rare and minimal due to use being topical. Sexual Dysfunction (uncommon), Breast abnormalities; skin reactions (frequency unknown), changes in menstrual cycles in women and potential effects on hormone-sensitive conditions. Driving and using machinery Using this product is not known to affect your ability to drive or use machinery. Continued use of application • You may need to use this medicine daily for at least 4 months before you see new hair growth, this is because hair growth is a slow process. • Hair growth may be soft and downy at the start but should eventually become the same as normal hair. • Once the hair has begun to re-grow, you need to continue using this medicine daily for the growth to continue. • When you stop using the medicine, the hair that has re-grown may disappear after 3-4 months and the balding / hair loss process will continue. • If you have no improvement in your hair growth after one year of use, you should discontinue treatment. • Your prescribing pharmacist will guide you each month and will monitor your hair growth progress.

Minoxidil 7% and Tretinoin 0.01% Topical Scalp Serum (Alcohol Free) The active ingredients in this formulation include Minoxidil 7% and Tretinoin 0.01% Topical Scalp Serum (Alcohol Free). Minoxidil is a potent vasodilator utilised in the treatment of hair loss and pattern baldness. It functions by enhancing blood circulation to the scalp, thereby stimulating hair growth. Tretinoin, a retinoid, enhances the penetration of minoxidil and may improve the health and function of the hair follicle. Making this formulation an effective treatment for conditions such as Alopecia, Androgenic Alopecia and Menopausal Female Pattern Hair Loss. This combination is best suited to those have have difficulty in growing hair in length, and those that have had hair loss due to a stress induced event. Personalised Hair Growth Treatments Ongoing Clinical Guidance and Support Medical Consultation Required Request Prescription Formula Information GrowBack's Minoxidil 7% and Tretinoin 0.01% Topical Scalp Serum (Alcohol Free) Scalp Serum is a specially compounded liquid formulation designed for topical application to the scalp. This unique blend of active ingredients is dispensed in a dropper bottle for precise and controlled administration, ensuring targeted treatment for a variety of hair loss and scalp conditions. Minoxidil, a potent vasodilator, works by increasing blood flow to the scalp, thereby stimulating hair growth. Minoxidil may stimulate the growth of human hairs by prolonging anagen through these proliferative and anti-apoptotic effects on dermal papillary cells (DPCs). Minoxidil, the second active ingredient, is a well-known vasodilator that has been proven to stimulate hair growth and slow balding. It functions by widening blood vessels and opening potassium channels, which allows more oxygen, blood, and nutrients to the follicle. This results in a revitalisation of shrunken hair follicles, increasing their size, and prolonging the growth phase of the hair cycle. Tretinoin, a derivative of vitamin A, is included at a 0.01% concentration. It promotes skin cell turnover and can help improve the skin's texture and tone. In the context of hair loss, tretinoin is believed to enhance the penetration of minoxidil, increasing its effectiveness. Supercharges Minoxidil to promote denser hair regrowth. This powerful combination formulation is an effective treatment for a range of hair loss and scalp conditions, including male and female pattern baldness, alopecia areata, and preventative hair loss. When used as directed, this formulation is safe and effective. It is important for patients to adhere to our prescribers instructions for use and not to exceed the recommended dosage. Potential side effects may include scalp irritation, dryness, and itching. It is recommended to consult with a healthcare professional if these or any other side effects occur. The carrier agent used to deliver the active ingredient to your scalp is free from the potentially harsh chemicals ethanol and propylene glycol. We opted for a highly spreadable hydrophilic solution containing mineral salts of vegetable origin (TrichoSol™). Making this an alcohol-free treatment. Base solution (TrichoSol™): Aqua, lactic Acid, polysorbate 80, lavandula officinalis water parfum phenoxyethanol, rosmarinus officinalis leaf oil, ethylhexylglycerin, BHT, juniperus communis fruit oil, juniperus virginiana wood oil, amyris balsamifera bark oil, lavandula angustifolia herb oil, melaleuca alternifolia leaf oil, eucalyptus globulus leaf oil. If you have any questions about GrowBack's Minoxidil 7% and Tretinoin 0.01% Topical Scalp Serum (Alcohol Free) Scalp Serum , please do not hesitate to contact us. Our team is here to provide the information and support you need. How Does It Work Minoxidil is a well-known vasodilator that is commonly used to treat hair loss. It works by widening blood vessels and opening potassium channels, which allows more oxygen, blood, and nutrients to reach the hair follicles. This action can stimulate hair growth and extend the growth phase of the hair cycle. Tretinoin, a derivative of vitamin A, is included at a 0.01% concentration. It promotes skin cell turnover and can help improve the skin's texture and tone. In the context of hair loss, tretinoin is believed to enhance the penetration of minoxidil, increasing its effectiveness. When Will I See Results? It usually takes months or years for you to lose hair, so it can take several weeks to GrowBack. 80% of our patients see results within 3-4 months. In the rare instance, that the results are not as desirable as you want, we can increase the strength or add other active ingredients based on your hair health profile. The best results will come from continued use of your recommended treatments and are seen after 4-6 months. You will need to maintain the treatment for continual growth and reduced hair shedding. Possible Side Effects Like all medicines, your Personalised Scalp Application can cause side effects, although not everybody gets them. Personalised Scalp Applications may cause the following side effects of unknown frequency (frequency cannot be estimated from the available data): • Skin irritation may occur. If this happens stop using the product. • Unwanted non-scalp hair has occasionally been reported. Always wash your hands thoroughly after application and if you accidentally apply the solution to parts of the body other than the scalp, rinse thoroughly with plenty of water. • Scalp irritation such as local redness, itchiness, dryness, flaky skin have all been reported. This may be due to propylene glycol in the product. This is usually only a temporary effect, but if it is persistent, you should stop using this product. • Temporary hair loss may occur during the first 2 – 6 weeks of use. This is likely to be because of a change within the growth cycle and it should stop within a couple of weeks. If this hair loss continues for longer than 2 weeks, stop using the product and talk to your prescribing pharmacist. • Change in hair colour and / or texture may occur. Please be aware that this treatment may take up to 4-6 months of regular use to show noticeable results. How To Use This formulation can be used by both men and women. Avoid if pregnant or breast feeding. If you are on any medication, please check with our clinical prescriber before using this formulation. Always perform a patch test before applying to the whole scalp. Apply a small amount of the scalp serum on your scalp and leave on for a few hours. Monitor and observe to check for any irritation, redness, itching or blistering. If there is of these reactions please contact us immediately. If no reactions have been observed then proceed to apply the scalp serum to the areas of treatment. On the first application only use half the dosage amount and leave overnight. If you haven't had any reactions then continue your treatment at full optimal dosing as instructed. To apply a solution medication, we recommend the following steps: 1. Part your hair down the middle of your head. Then, use a dropper to apply the medication along the part, from the front of your scalp to the back. Make sure you continuously, but gently squeeze out small amounts of the medication as you work your way along the part with the dropper. 2. Part your hair a second and third time to the right and left of your middle part, about 2 inches down. Continuously apply the medication along each part from the front of your scalp to the back. 3. Part your hair a fourth and fifth time just above your right and left ears. Continuously apply the medication along each part from the front of your scalp to the back. Safety Information Talk to your prescriber: • If you suffer from heart disease, including abnormal heart rhythms or rates, angina, or chest pains and / or circulation disorders. • If you are at all unsure whether your scalp is normal and healthy. • If you, or a close relative, are suffering or has suffered cancer. • If you have had any allergic reactions to any applications. • If you are pregnant, breast feeding or are planning a family. • If you are unsure of why you have been prescribed this formula. Take special care when using this product: • Keep the product away from your eyes and mouth. • Wash your hands straight after application. • Before first use, perform a patch test as explained in initial consultation. • Store product as per dispensing label instructions. • Use pipette to measure doses. One dose is equivalent to 1ml. • Do not exceed 2ml within 24 hours. Side Effects – 17-alpha Estradiol - Generally the side effects are mild and localised at application site. These side effects below are rare and minimal due to use being topical. Sexual Dysfunction (uncommon), Breast abnormalities; skin reactions (frequency unknown), changes in menstrual cycles in women and potential effects on hormone-sensitive conditions. Driving and using machinery Using this product is not known to affect your ability to drive or use machinery. Continued use of application • You may need to use this medicine daily for at least 4 months before you see new hair growth, this is because hair growth is a slow process. • Hair growth may be soft and downy at the start but should eventually become the same as normal hair. • Once the hair has begun to re-grow, you need to continue using this medicine daily for the growth to continue. • When you stop using the medicine, the hair that has re-grown may disappear after 3-4 months and the balding / hair loss process will continue. • If you have no improvement in your hair growth after one year of use, you should discontinue treatment. • Your prescribing pharmacist will guide you each month and will monitor your hair growth progress.

Minoxidil 7%, Cetirizine 2% and Melatonin 2% Topical Scalp Serum (Alcohol Free) The active ingredients in this formulation include Minoxidil 7%, Cetirizine 2% and Melatonin 2% Topical Scalp Serum (Alcohol Free). Minoxidil is a potent vasodilator utilised in the treatment of hair loss and pattern baldness. It functions by enhancing blood circulation to the scalp, thereby stimulating hair growth. Cetirizine inhibits release of prostaglandin D2 and stimulates the release of prostaglandin E2. This combination of activity makes Cetirizine a powerful hair growth stimulator. Melatonin is included for its anti-inflammatory, DHT blocking and antioxidant effects, which can help repair and rejuvenate the skin. Making this formulation an effective treatment for conditions such as Alopecia, Androgenic Alopecia and Menopausal Female Pattern Hair Loss. This combination is best suited to those have have difficulty in growing hair in length, and those that have had hair loss due to a stress induced event. Personalised Hair Growth Treatments Ongoing Clinical Guidance and Support Medical Consultation Required Request Prescription Formula Information GrowBack's Minoxidil 7%, Cetirizine 2% and Melatonin 2% Topical Scalp Serum (Alcohol Free) Scalp Serum is a specially compounded liquid formulation designed for topical application to the scalp. This unique blend of active ingredients is dispensed in a dropper bottle for precise and controlled administration, ensuring targeted treatment for a variety of hair loss and scalp conditions. Minoxidil, a potent vasodilator, works by increasing blood flow to the scalp, thereby stimulating hair growth. Minoxidil may stimulate the growth of human hairs by prolonging anagen through these proliferative and anti-apoptotic effects on dermal papillary cells (DPCs). Minoxidil, the second active ingredient, is a well-known vasodilator that has been proven to stimulate hair growth and slow balding. It functions by widening blood vessels and opening potassium channels, which allows more oxygen, blood, and nutrients to the follicle. This results in a revitalisation of shrunken hair follicles, increasing their size, and prolonging the growth phase of the hair cycle. Cetirizine inhibits release of prostaglandin D2 and stimulates the release of prostaglandin E2. This combination of activity makes Cetirizine a powerful hair growth stimulator. Prostaglandins, particularly certain types such as prostaglandin D2 (PGD2) and prostaglandin E2 (PGE2), have been found to play a role in regulating hair follicle function. Melatonin, a powerful antioxidant, protects the scalp from oxidative damage that can lead to hair loss, aids in reducing inflammation, blocks dihydratestosterone (DHT) and aids in promoting healthy skin cells on the scalp. This powerful combination formulation is an effective treatment for a range of hair loss and scalp conditions, including male and female pattern baldness, alopecia areata, and preventative hair loss. When used as directed, this formulation is safe and effective. It is important for patients to adhere to our prescribers instructions for use and not to exceed the recommended dosage. Potential side effects may include scalp irritation, dryness, and itching. It is recommended to consult with a healthcare professional if these or any other side effects occur. The carrier agent used to deliver the active ingredient to your scalp is free from the potentially harsh chemicals ethanol and propylene glycol. We opted for a highly spreadable hydrophilic solution containing mineral salts of vegetable origin (TrichoSol™). Making this an alcohol-free treatment. Base solution (TrichoSol™): Aqua, lactic Acid, polysorbate 80, lavandula officinalis water parfum phenoxyethanol, rosmarinus officinalis leaf oil, ethylhexylglycerin, BHT, juniperus communis fruit oil, juniperus virginiana wood oil, amyris balsamifera bark oil, lavandula angustifolia herb oil, melaleuca alternifolia leaf oil, eucalyptus globulus leaf oil. If you have any questions about GrowBack's Minoxidil 7%, Cetirizine 2% and Melatonin 2% Topical Scalp Serum (Alcohol Free) Scalp Serum , please do not hesitate to contact us. Our team is here to provide the information and support you need. How Does It Work Minoxidil is a well-known vasodilator that is commonly used to treat hair loss. It works by widening blood vessels and opening potassium channels, which allows more oxygen, blood, and nutrients to reach the hair follicles. This action can stimulate hair growth and extend the growth phase of the hair cycle. Cetirizine inhibits release of prostaglandin D2 and stimulates the release of prostaglandin E2. This combination of activity makes Cetirizine a powerful hair growth stimulator. Prostaglandins, particularly certain types such as prostaglandin D2 (PGD2) and prostaglandin E2 (PGE2), have been found to play a role in regulating hair follicle function. Cetirizine by mechanism is an anti-inflammatory medication. Cetirizine also leads to a reduction in prostaglandins that have been well documented in the hair loss pathway, as well as inflammation cascade. By using cetirizine to block these pathways, inflammatory symptoms such as itching, redness, warmth, etc. can be reduced. Researchers studied the use of topical cetirizine in patients with androgenetic alopecia (non-scarring hair loss) and found that it increased hair density and hair diameters. Melatonin, a powerful antioxidant, protects the scalp from oxidative damage that can lead to hair loss, aids in reducing inflammation, blocks dihydrotestosterone (DHT) and aids in promoting healthy skin cells on the scalp. When Will I See Results? It usually takes months or years for you to lose hair, so it can take several weeks to GrowBack. 80% of our patients see results within 3-4 months. In the rare instance, that the results are not as desirable as you want, we can increase the strength or add other active ingredients based on your hair health profile. The best results will come from continued use of your recommended treatments and are seen after 4-6 months. You will need to maintain the treatment for continual growth and reduced hair shedding. Possible Side Effects Like all medicines, your Personalised Scalp Application can cause side effects, although not everybody gets them. Personalised Scalp Applications may cause the following side effects of unknown frequency (frequency cannot be estimated from the available data): • Skin irritation may occur. If this happens stop using the product. • Unwanted non-scalp hair has occasionally been reported. Always wash your hands thoroughly after application and if you accidentally apply the solution to parts of the body other than the scalp, rinse thoroughly with plenty of water. • Scalp irritation such as local redness, itchiness, dryness, flaky skin have all been reported. This may be due to propylene glycol in the product. This is usually only a temporary effect, but if it is persistent, you should stop using this product. • Temporary hair loss may occur during the first 2 – 6 weeks of use. This is likely to be because of a change within the growth cycle and it should stop within a couple of weeks. If this hair loss continues for longer than 2 weeks, stop using the product and talk to your prescribing pharmacist. • Change in hair colour and / or texture may occur. Please be aware that this treatment may take up to 4-6 months of regular use to show noticeable results. How To Use This formulation can be used by both men and women. Avoid if pregnant or breast feeding. If you are on any medication, please check with our clinical prescriber before using this formulation. Always perform a patch test before applying to the whole scalp. Apply a small amount of the scalp serum on your scalp and leave on for a few hours. Monitor and observe to check for any irritation, redness, itching or blistering. If there is of these reactions please contact us immediately. If no reactions have been observed then proceed to apply the scalp serum to the areas of treatment. On the first application only use half the dosage amount and leave overnight. If you haven't had any reactions then continue your treatment at full optimal dosing as instructed. To apply a solution medication, we recommend the following steps: 1. Part your hair down the middle of your head. Then, use a dropper to apply the medication along the part, from the front of your scalp to the back. Make sure you continuously, but gently squeeze out small amounts of the medication as you work your way along the part with the dropper. 2. Part your hair a second and third time to the right and left of your middle part, about 2 inches down. Continuously apply the medication along each part from the front of your scalp to the back. 3. Part your hair a fourth and fifth time just above your right and left ears. Continuously apply the medication along each part from the front of your scalp to the back. Safety Information Talk to your prescriber: • If you suffer from heart disease, including abnormal heart rhythms or rates, angina, or chest pains and / or circulation disorders. • If you are at all unsure whether your scalp is normal and healthy. • If you, or a close relative, are suffering or has suffered cancer. • If you have had any allergic reactions to any applications. • If you are pregnant, breast feeding or are planning a family. • If you are unsure of why you have been prescribed this formula. Take special care when using this product: • Keep the product away from your eyes and mouth. • Wash your hands straight after application. • Before first use, perform a patch test as explained in initial consultation. • Store product as per dispensing label instructions. • Use pipette to measure doses. One dose is equivalent to 1ml. • Do not exceed 2ml within 24 hours. Side Effects – 17-alpha Estradiol - Generally the side effects are mild and localised at application site. These side effects below are rare and minimal due to use being topical. Sexual Dysfunction (uncommon), Breast abnormalities; skin reactions (frequency unknown), changes in menstrual cycles in women and potential effects on hormone-sensitive conditions. Driving and using machinery Using this product is not known to affect your ability to drive or use machinery. Continued use of application • You may need to use this medicine daily for at least 4 months before you see new hair growth, this is because hair growth is a slow process. • Hair growth may be soft and downy at the start but should eventually become the same as normal hair. • Once the hair has begun to re-grow, you need to continue using this medicine daily for the growth to continue. • When you stop using the medicine, the hair that has re-grown may disappear after 3-4 months and the balding / hair loss process will continue. • If you have no improvement in your hair growth after one year of use, you should discontinue treatment. • Your prescribing pharmacist will guide you each month and will monitor your hair growth progress.

Minoxidil 5%, Caffiene 2% and 17-a Estradiol 0.05% Topical Scalp Serum (Alcohol Free) The active ingredients in this formulation include Minoxidil 5%, Caffiene 2% and 17-a Estradiol 0.05%. Minoxidil 5% is a potent vasodilator utilised in the treatment of hair loss and pattern baldness. It functions by enhancing blood circulation to the scalp, thereby stimulating hair growth. Caffeine 2%, is known for its anti-inflammatory and antioxidant properties. Caffeine stimulates blood flow and reduces inflammation. Caffeine stimulates blood flow and reduces inflammation. Caffeine, is known for its anti-inflammatory and antioxidant properties, making it an effective treatment for conditions such as Alopecia, Androgenic Alopecia, Telogen Effluvium, Trichotillomania, and Female Pattern Hair Loss. 17-alpha Estradiol inhibits the conversion of testosterone to the metabolite dihydrotestosterone (DHT) by suppressing5AR activity. In addition, by inhibiting dehydrogenase, it reduces the conversion process of androstenedione to testosterone, resulting in a reduction in the synthesis of testosterone and DHT. Making this formulation an effective treatment for conditions such as Alopecia, Androgenic Alopecia and Menopausal Female Pattern Hair Loss. Personalised Hair Growth Treatments Ongoing Clinical Guidance and Support Medical Consultation Required Request Prescription Formula Information GrowBack's Minoxidil 5%, Caffiene 2% and 17-a Estradiol 0.05% Scalp Serum is a specially compounded liquid formulation designed for topical application to the scalp. This unique blend of active ingredients is dispensed in a dropper bottle for precise and controlled administration, ensuring targeted treatment for a variety of hair loss and scalp conditions. Minoxidil, a potent vasodilator, works by increasing blood flow to the scalp, thereby stimulating hair growth. Minoxidil may stimulate the growth of human hairs by prolonging anagen through these proliferative and anti-apoptotic effects on dermal papillary cells (DPCs). Minoxidil, the second active ingredient, is a well-known vasodilator that has been proven to stimulate hair growth and slow balding. It functions by widening blood vessels and opening potassium channels, which allows more oxygen, blood, and nutrients to the follicle. This results in a revitalisation of shrunken hair follicles, increasing their size, and prolonging the growth phase of the hair cycle. Caffeine, is known for its anti-inflammatory and antioxidant properties, making it an effective treatment for conditions such as Alopecia, Androgenic Alopecia, Telogen Effluvium, Trichotillomania, and Female Pattern Hair Loss. 17-alpha Estradiol inhibits the conversion of testosterone to the metabolite dihydrotestosterone (DHT) by suppressing5AR activity. In addition, by inhibiting dehydrogenase, it reduces the conversion process of androstenedione to testosterone, resulting in a reduction in the synthesis of testosterone and DHT. This powerful combination formulation is an effective treatment for a range of hair loss and scalp conditions, including male and female pattern baldness, alopecia areata, and preventative hair loss. When used as directed, this formulation is safe and effective. It is important for patients to adhere to our prescribers instructions for use and not to exceed the recommended dosage. Potential side effects may include scalp irritation, dryness, and itching. It is recommended to consult with a healthcare professional if these or any other side effects occur. The carrier agent used to deliver the active ingredient to your scalp is free from the potentially harsh chemicals ethanol and propylene glycol. We opted for a highly spreadable hydrophilic solution containing mineral salts of vegetable origin (TrichoSol™). Making this an alcohol-free treatment. Base solution (TrichoSol™): Aqua, lactic Acid, polysorbate 80, lavandula officinalis water parfum phenoxyethanol, rosmarinus officinalis leaf oil, ethylhexylglycerin, BHT, juniperus communis fruit oil, juniperus virginiana wood oil, amyris balsamifera bark oil, lavandula angustifolia herb oil, melaleuca alternifolia leaf oil, eucalyptus globulus leaf oil. If you have any questions about GrowBack's Minoxidil 5%, Caffiene 2% and 17-a Estradiol 0.05% Scalp Serum , please do not hesitate to contact us. Our team is here to provide the information and support you need. How Does It Work Minoxidil is a well-known vasodilator that is commonly used to treat hair loss. It works by widening blood vessels and opening potassium channels, which allows more oxygen, blood, and nutrients to reach the hair follicles. This action can stimulate hair growth and extend the growth phase of the hair cycle. Caffeine, is known for its anti-inflammatory and antioxidant properties, making it an effective treatment for conditions such as Alopecia, Androgenic Alopecia, Telogen Effluvium, Trichotillomania, and Female Pattern Hair Loss. 17-alpha Estradiol inhibits the conversion of testosterone to the metabolite dihydrotestosterone (DHT) by suppressing 5AR activity. In addition, by inhibiting dehydrogenase, it reduces the conversion process of androstenedione to testosterone, resulting in a reduction in the synthesis of testosterone and DHT. Possible Side Effects Like all medicines, your Personalised Scalp Application can cause side effects, although not everybody gets them. Personalised Scalp Applications may cause the following side effects of unknown frequency (frequency cannot be estimated from the available data): • Skin irritation may occur. If this happens stop using the product. • Unwanted non-scalp hair has occasionally been reported. Always wash your hands thoroughly after application and if you accidentally apply the solution to parts of the body other than the scalp, rinse thoroughly with plenty of water. • Scalp irritation such as local redness, itchiness, dryness, flaky skin have all been reported. This may be due to propylene glycol in the product. This is usually only a temporary effect, but if it is persistent, you should stop using this product. • Temporary hair loss may occur during the first 2 – 6 weeks of use. This is likely to be because of a change within the growth cycle and it should stop within a couple of weeks. If this hair loss continues for longer than 2 weeks, stop using the product and talk to your prescribing pharmacist. • Change in hair colour and / or texture may occur. Please be aware that this treatment may take up to 4-6 months of regular use to show noticeable results. How To Use This formulation can be used by both men and women. Avoid if pregnant or breast feeding. If you are on any medication, please check with our clinical prescriber before using this formulation. Always perform a patch test before applying to the whole scalp. Apply a small amount of the scalp serum on your scalp and leave on for a few hours. Monitor and observe to check for any irritation, redness, itching or blistering. If there is of these reactions please contact us immediately. If no reactions have been observed then proceed to apply the scalp serum to the areas of treatment. On the first application only use half the dosage amount and leave overnight. If you haven't had any reactions then continue your treatment at full optimal dosing as instructed. To apply a solution medication, we recommend the following steps: 1. Part your hair down the middle of your head. Then, use a dropper to apply the medication along the part, from the front of your scalp to the back. Make sure you continuously, but gently squeeze out small amounts of the medication as you work your way along the part with the dropper. 2. Part your hair a second and third time to the right and left of your middle part, about 2 inches down. Continuously apply the medication along each part from the front of your scalp to the back. 3. Part your hair a fourth and fifth time just above your right and left ears. Continuously apply the medication along each part from the front of your scalp to the back. Safety Information Talk to your prescriber: • If you suffer from heart disease, including abnormal heart rhythms or rates, angina, or chest pains and / or circulation disorders. • If you are at all unsure whether your scalp is normal and healthy. • If you, or a close relative, are suffering or has suffered cancer. • If you have had any allergic reactions to any applications. • If you are pregnant, breast feeding or are planning a family. • If you are unsure of why you have been prescribed this formula. Take special care when using this product: • Keep the product away from your eyes and mouth. • Wash your hands straight after application. • Before first use, perform a patch test as explained in initial consultation. • Store product as per dispensing label instructions. • Use pipette to measure doses. One dose is equivalent to 1ml. • Do not exceed 2ml within 24 hours. Side Effects – Dutasteride Sexual Dysfunction (uncommon), Breast abnormalities; skin reactions (frequency unknown), Angioedema; depression; infertility male; palpitations; testicular pain. Conception and Contraception Dutasteride is excreted in semen and use of a condom is recommended if sexual partner is pregnant or likely to become pregnant Driving and using machinery Using this product is not known to affect your ability to drive or use machinery. Continued use of application • You may need to use this medicine daily for at least 4 months before you see new hair growth, this is because hair growth is a slow process. • Hair growth may be soft and downy at the start but should eventually become the same as normal hair. • Once the hair has begun to re-grow, you need to continue using this medicine daily for the growth to continue. • When you stop using the medicine, the hair that has re-grown may disappear after 3-4 months and the balding / hair loss process will continue. • If you have no improvement in your hair growth after one year of use, you should discontinue treatment. • Your prescribing pharmacist will guide you each month and will monitor your hair growth progress.

Prostaquinon 3% & Dutasteride 0.25% Topical Scalp Serum (Alcohol Free) The active ingredients in this formulation include Prostaquinon 3% & Dutasteride 0.25% Topical Scalp Serum (Alcohol Free). Prostaquinon exerts anti-inflammatory and anti-oxidant effects and counteracts miniaturisation of hair follicles. Dutasteride, a 5-alpha-reductase inhibitor, works by preventing the conversion of testosterone to dihydrotestosterone (DHT), a hormone that can shrink hair follicles and lead to hair loss. Making this formulation an effective treatment for conditions such as Alopecia, Androgenic Alopecia and Menopausal Female Pattern Hair Loss. Personalised Hair Growth Treatments Ongoing Clinical Guidance and Support Medical Consultation Required Request Prescription Formula Information GrowBack's Prostaquinon 3% & Dutasteride 0.25% Topical Scalp Serum (Alcohol Free) Scalp Serum is a specially compounded liquid formulation designed for topical application to the scalp. This unique blend of active ingredients is dispensed in a dropper bottle for precise and controlled administration, ensuring targeted treatment for a variety of hair loss and scalp conditions. Prostaquinon® is a specialised raw material from Fagron that exerts significant anti-inflammatory and antioxidant effects, which are crucial in maintaining healthy hair follicles and promoting hair growth. By counteracting the miniaturisation of hair follicles, Prostaquinon® helps prevent the progression of hair thinning and loss. A key mechanism of its action is the inhibition of prostaglandin PGD2, a compound that recent studies have shown to be elevated in individuals with alopecia. PGD2 has been linked to the suppression of hair growth and the promotion of hair follicle regression. By inhibiting PGD2, Prostaquinon® not only helps to sustain the anagen (growth) phase of the hair cycle but also supports overall scalp health by reducing inflammation and oxidative stress. These combined effects make Prostaquinon® a valuable ingredient in formulations aimed at treating and preventing hair loss, offering a multifaceted approach to enhancing hair density and vitality. Dutasteride, a potent 5-alpha-reductase inhibitor, works by preventing the conversion of testosterone to dihydrotestosterone (DHT), a hormone that can shrink hair follicles and lead to hair loss. This makes it an effective component for treating conditions like androgenetic alopecia, commonly known as male or female pattern baldness. This powerful combination formulation is an effective treatment for a range of hair loss and scalp conditions, including male and female pattern baldness, alopecia areata, and preventative hair loss. When used as directed, this formulation is safe and effective. It is important for patients to adhere to our prescribers instructions for use and not to exceed the recommended dosage. Potential side effects may include scalp irritation, dryness, and itching. It is recommended to consult with a healthcare professional if these or any other side effects occur. The carrier agent used to deliver the active ingredient to your scalp is free from the potentially harsh chemicals ethanol and propylene glycol. We opted for a highly spreadable hydrophilic solution containing mineral salts of vegetable origin (TrichoSol™). Making this an alcohol-free treatment. Base solution (TrichoSol™): Aqua, lactic Acid, polysorbate 80, lavandula officinalis water parfum phenoxyethanol, rosmarinus officinalis leaf oil, ethylhexylglycerin, BHT, juniperus communis fruit oil, juniperus virginiana wood oil, amyris balsamifera bark oil, lavandula angustifolia herb oil, melaleuca alternifolia leaf oil, eucalyptus globulus leaf oil. If you have any questions about GrowBack's Prostaquinon 3% & Dutasteride 0.25% Topical Scalp Serum (Alcohol Free) Scalp Serum , please do not hesitate to contact us. Our team is here to provide the information and support you need. How Does It Work Prostaquinon exerts anti-inflammatory and anti-oxidant effects and counteracts miniaturisation of hair follicles. Dutasteride is a 5-alpha-reductase inhibitor, which works by blocking the conversion of testosterone to dihydrotestosterone (DHT), a hormone that can shrink hair follicles and lead to hair loss. By inhibiting this conversion, dutasteride helps to prevent further hair loss and may promote hair regrowth in some patients. The concentration in this formulation is intended to target the hair follicles topically, minimising systemic absorption and potential side effects. When Will I See Results? It usually takes months or years for you to lose hair, so it can take several weeks to GrowBack. 80% of our patients see results within 3-4 months. In the rare instance, that the results are not as desirable as you want, we can increase the strength or add other active ingredients based on your hair health profile. The best results will come from continued use of your recommended treatments and are seen after 4-6 months. You will need to maintain the treatment for continual growth and reduced hair shedding. Possible Side Effects Like all medicines, your Personalised Scalp Application can cause side effects, although not everybody gets them. Personalised Scalp Applications may cause the following side effects of unknown frequency (frequency cannot be estimated from the available data): • Skin irritation may occur. If this happens stop using the product. • Unwanted non-scalp hair has occasionally been reported. Always wash your hands thoroughly after application and if you accidentally apply the solution to parts of the body other than the scalp, rinse thoroughly with plenty of water. • Scalp irritation such as local redness, itchiness, dryness, flaky skin have all been reported. This may be due to propylene glycol in the product. This is usually only a temporary effect, but if it is persistent, you should stop using this product. • Temporary hair loss may occur during the first 2 – 6 weeks of use. This is likely to be because of a change within the growth cycle and it should stop within a couple of weeks. If this hair loss continues for longer than 2 weeks, stop using the product and talk to your prescribing pharmacist. • Change in hair colour and / or texture may occur. Please be aware that this treatment may take up to 4-6 months of regular use to show noticeable results. Side Effects – Finasteride and Dutasteride Sexual Dysfunction (uncommon), Breast abnormalities; skin reactions (frequency unknown), Angioedema; depression; infertility male; palpitations; testicular pain. Conception and Contraception Finasteride and Dutasteride is excreted in semen and use of a condom is recommended if sexual partner is pregnant or likely to become pregnant How To Use This formulation can be used by both men and women. Avoid if pregnant or breast feeding. If you are on any medication, please check with our clinical prescriber before using this formulation. Always perform a patch test before applying to the whole scalp. Apply a small amount of the scalp serum on your scalp and leave on for a few hours. Monitor and observe to check for any irritation, redness, itching or blistering. If there is of these reactions please contact us immediately. If no reactions have been observed then proceed to apply the scalp serum to the areas of treatment. On the first application only use half the dosage amount and leave overnight. If you haven't had any reactions then continue your treatment at full optimal dosing as instructed. To apply a solution medication, we recommend the following steps: 1. Part your hair down the middle of your head. Then, use a dropper to apply the medication along the part, from the front of your scalp to the back. Make sure you continuously, but gently squeeze out small amounts of the medication as you work your way along the part with the dropper. 2. Part your hair a second and third time to the right and left of your middle part, about 2 inches down. Continuously apply the medication along each part from the front of your scalp to the back. 3. Part your hair a fourth and fifth time just above your right and left ears. Continuously apply the medication along each part from the front of your scalp to the back. Safety Information Talk to your prescriber: • If you suffer from heart disease, including abnormal heart rhythms or rates, angina, or chest pains and / or circulation disorders. • If you are at all unsure whether your scalp is normal and healthy. • If you, or a close relative, are suffering or has suffered cancer. • If you have had any allergic reactions to any applications. • If you are pregnant, breast feeding or are planning a family. • If you are unsure of why you have been prescribed this formula. Take special care when using this product: • Keep the product away from your eyes and mouth. • Wash your hands straight after application. • Before first use, perform a patch test as explained in initial consultation. • Store product as per dispensing label instructions. • Use pipette to measure doses. One dose is equivalent to 1ml. • Do not exceed 2ml within 24 hours. Side Effects – 17-alpha Estradiol - Generally the side effects are mild and localised at application site. These side effects below are rare and minimal due to use being topical. Sexual Dysfunction (uncommon), Breast abnormalities; skin reactions (frequency unknown), changes in menstrual cycles in women and potential effects on hormone-sensitive conditions. Driving and using machinery Using this product is not known to affect your ability to drive or use machinery. Continued use of application • You may need to use this medicine daily for at least 4 months before you see new hair growth, this is because hair growth is a slow process. • Hair growth may be soft and downy at the start but should eventually become the same as normal hair. • Once the hair has begun to re-grow, you need to continue using this medicine daily for the growth to continue. • When you stop using the medicine, the hair that has re-grown may disappear after 3-4 months and the balding / hair loss process will continue. • If you have no improvement in your hair growth after one year of use, you should discontinue treatment. • Your prescribing pharmacist will guide you each month and will monitor your hair growth progress.

Minoxidil 5%, Tretinoin 0.05%, Melatonin 1% and 17-alpha Estradiol 0.05% Topical Scalp Serum (Alcohol Free) The active ingredients in this formulation include Minoxidil 5%, Tretinoin 0.05%, Melatonin 1% and 17-alpha Estradiol 0.05%. Minoxidil is a potent vasodilator utilised in the treatment of hair loss and pattern baldness. It functions by enhancing blood circulation to the scalp, thereby stimulating hair growth. Tretinoin, a retinoid, enhances the penetration of minoxidil and may improve the health and function of the hair follicle. Melatonin is included for its anti-inflammatory, DHT blocking and antioxidant effects, which can help repair and rejuvenate the skin. 17-alpha Estradiol inhibits the conversion of testosterone to the metabolite dihydrotestosterone (DHT) by suppressing 5AR activity. In addition, by inhibiting dehydrogenase, it reduces the conversion process of androstenedione to testosterone, resulting in a reduction in the synthesis of testosterone and DHT. Personalised Hair Growth Treatments Ongoing Clinical Guidance and Support Medical Consultation Required Request Prescription Formula Information GrowBack’s Minoxidil 5%, Tretinoin 0.05%, Melatonin 1% and 17-alpha Estradiol 0.05% Scalp Serum is a specially compounded liquid formulation designed for topical application to the scalp. This unique blend of active ingredients is dispensed in a dropper bottle for precise and controlled administration, ensuring targeted treatment for a variety of hair loss and scalp conditions. Minoxidil, a potent vasodilator, works by increasing blood flow to the scalp, thereby stimulating hair growth. Minoxidil may stimulate the growth of human hairs by prolonging anagen through these proliferative and anti-apoptotic effects on dermal papillary cells (DPCs). Minoxidil, the second active ingredient, is a well-known vasodilator that has been proven to stimulate hair growth and slow balding. It functions by widening blood vessels and opening potassium channels, which allows more oxygen, blood, and nutrients to the follicle. This results in a revitalisation of shrunken hair follicles, increasing their size, and prolonging the growth phase of the hair cycle. Melatonin, a powerful antioxidant, protects the scalp from oxidative damage that can lead to hair loss, aids in reducing inflammation, blocks dihydratestosterone (DHT) and aids in promoting healthy skin cells on the scalp. Tretinoin, a derivative of vitamin A, is included at a 0.05% concentration. It promotes skin cell turnover and can help improve the skin's texture and tone. In the context of hair loss, tretinoin is believed to enhance the penetration of minoxidil, increasing its effectiveness. Supercharges Minoxidil to promote denser hair regrowth. 17-alpha Estradiol inhibits the conversion of testosterone to the metabolite dihydrotestosterone (DHT) by suppressing 5AR activity. In addition, by inhibiting dehydrogenase, it reduces the conversion process of androstenedione to testosterone, resulting in a reduction in the synthesis of testosterone and DHT. How Does It Work Minoxidil is a well-known vasodilator that is commonly used to treat hair loss. It works by widening blood vessels and opening potassium channels, which allows more oxygen, blood, and nutrients to reach the hair follicles. This action can stimulate hair growth and extend the growth phase of the hair cycle. Tretinoin, a derivative of vitamin A, is included at a 0.01% concentration. It promotes skin cell turnover and can help improve the skin's texture and tone. In the context of hair loss, tretinoin is believed to enhance the penetration of minoxidil, increasing its effectiveness. Melatonin, a powerful antioxidant, protects the scalp from oxidative damage that can lead to hair loss, aids in reducing inflammation, blocks dihydratestosterone (DHT) and aids in promoting healthy skin cells on the scalp. 17-alpha Estradiol inhibits the conversion of testosterone to the metabolite dihydrotestosterone (DHT) by suppressing 5AR activity. In addition, by inhibiting dehydrogenase, it reduces the conversion process of androstenedione to testosterone, resulting in a reduction in the synthesis of testosterone and DHT. Possible Side Effects Like all medicines, your Personalised Scalp Application can cause side effects, although not everybody gets them. Personalised Scalp Applications may cause the following side effects of unknown frequency (frequency cannot be estimated from the available data): • Skin irritation may occur. If this happens stop using the product. • Unwanted non-scalp hair has occasionally been reported. Always wash your hands thoroughly after application and if you accidentally apply the solution to parts of the body other than the scalp, rinse thoroughly with plenty of water. • Scalp irritation such as local redness, itchiness, dryness, flaky skin have all been reported. This may be due to propylene glycol in the product. This is usually only a temporary effect, but if it is persistent, you should stop using this product. • Temporary hair loss may occur during the first 2 – 6 weeks of use. This is likely to be because of a change within the growth cycle and it should stop within a couple of weeks. If this hair loss continues for longer than 2 weeks, stop using the product and talk to your prescribing pharmacist. • Change in hair colour and / or texture may occur. Please be aware that this treatment may take up to 4-6 months of regular use to show noticeable results. When Will I See Results? It usually takes months or years for you to lose hair, so it can take several weeks to GrowBack. 80% of our patients see results within 3-4 months. In the rare instance, that the results are not as desirable as you want, we can increase the strength or add other active ingredients based on your hair health profile. The best results will come from continued use of your recommended treatments and are seen after 4-6 months. You will need to maintain the treatment for continual growth and reduced hair shedding. How To Use This formulation can be used by both men and women. Avoid if pregnant or breast feeding. If you are on any medication, please check with our clinical prescriber before using this formulation. Always perform a patch test before applying to the whole scalp. Apply a small amount of the scalp serum on your scalp and leave on for a few hours. Monitor and observe to check for any irritation, redness, itching or blistering. If there is of these reactions please contact us immediately. If no reactions have been observed then proceed to apply the scalp serum to the areas of treatment. On the first application only use half the dosage amount and leave overnight. If you haven't had any reactions then continue your treatment at full optimal dosing as instructed. To apply a solution medication, we recommend the following steps: 1. Part your hair down the middle of your head. Then, use a dropper to apply the medication along the part, from the front of your scalp to the back. Make sure you continuously, but gently squeeze out small amounts of the medication as you work your way along the part with the dropper. 2. Part your hair a second and third time to the right and left of your middle part, about 2 inches down. Continuously apply the medication along each part from the front of your scalp to the back. 3. Part your hair a fourth and fifth time just above your right and left ears. Continuously apply the medication along each part from the front of your scalp to the back. Safety Information Talk to your prescriber: • If you suffer from heart disease, including abnormal heart rhythms or rates, angina, or chest pains and / or circulation disorders. • If you are at all unsure whether your scalp is normal and healthy. • If you, or a close relative, are suffering or has suffered cancer. • If you have had any allergic reactions to any applications. • If you are pregnant, breast feeding or are planning a family. • If you are unsure of why you have been prescribed this formula. Take special care when using this product: • Keep the product away from your eyes and mouth. • Wash your hands straight after application. • Before first use, perform a patch test as explained in initial consultation. • Store product as per dispensing label instructions. • Use pipette to measure doses. One dose is equivalent to 1ml. • Do not exceed 2ml within 24 hours. Driving and using machinery Using this product is not known to affect your ability to drive or use machinery. Continued use of application • You may need to use this medicine daily for at least 4 months before you see new hair growth, this is because hair growth is a slow process. • Hair growth may be soft and downy at the start but should eventually become the same as normal hair. • Once the hair has begun to re-grow, you need to continue using this medicine daily for the growth to continue. • When you stop using the medicine, the hair that has re-grown may disappear after 3-4 months and the balding / hair loss process will continue. • If you have no improvement in your hair growth after one year of use, you should discontinue treatment. • Your prescribing pharmacist will guide you each month and will monitor your hair growth progress.

Minoxidil 5%, Finasteride 0.25% and Tretinoin 0.01% Topical Scalp Serum (Alcohol Free) The active ingredients in this formulation include Minoxidil 5%, Finasteride 0.25% and Tretinoin 0.01%. Minoxidil 5% is a potent vasodilator utilised in the treatment of hair loss and pattern baldness. It functions by enhancing blood circulation to the scalp, thereby stimulating hair growth. Finasteride 0.1% is a type 2 5-alpha-reductase inhibitor that reduces the conversion of testosterone to dihydrotestosterone (DHT), a hormone known to contribute to hair follicle miniaturisation and hair loss. Tretinoin 0.01%, a retinoid, enhances the penetration of minoxidil and may improve the health and function of the hair follicle. Making this formulation an effective treatment for conditions such as Alopecia, Androgenic Alopecia and Menopausal Female Pattern Hair Loss. Personalised Hair Growth Treatments Ongoing Clinical Guidance and Support Medical Consultation Required Request Prescription Formula Information GrowBack's Minoxidil 5%, Finasteride 0.25% and Tretinoin 0.01% Scalp Serum is a specially compounded liquid formulation designed for topical application to the scalp. This unique blend of active ingredients is dispensed in a dropper bottle for precise and controlled administration, ensuring targeted treatment for a variety of hair loss and scalp conditions. Minoxidil, a potent vasodilator, works by increasing blood flow to the scalp, thereby stimulating hair growth. Minoxidil may stimulate the growth of human hairs by prolonging anagen through these proliferative and anti-apoptotic effects on dermal papillary cells (DPCs). Minoxidil, the second active ingredient, is a well-known vasodilator that has been proven to stimulate hair growth and slow balding. It functions by widening blood vessels and opening potassium channels, which allows more oxygen, blood, and nutrients to the follicle. This results in a revitalisation of shrunken hair follicles, increasing their size, and prolonging the growth phase of the hair cycle. Finasteride 0.1% is a type of medication known as a 5-alpha-reductase inhibitor. It works by targeting the enzyme 5-alpha-reductase, which is responsible for the conversion of testosterone to dihydrotestosterone (DHT). DHT is a hormone that has been implicated in the miniaturisation of hair follicles, leading to hair loss. By inhibiting this enzyme, finasteride effectively reduces DHT levels in the scalp, which helps to halt the progression of hair loss and in some cases, may even reverse it by allowing hair follicles to regain their normal size and function. Tretinoin, a derivative of vitamin A, is included at a 0.01% concentration. It promotes skin cell turnover and can help improve the skin's texture and tone. In the context of hair loss, tretinoin is believed to enhance the penetration of minoxidil, increasing its effectiveness. Supercharges Minoxidil to promote denser hair regrowth. This powerful combination formulation is an effective treatment for a range of hair loss and scalp conditions, including male and female pattern baldness, alopecia areata, and preventative hair loss. When used as directed, this formulation is safe and effective. It is important for patients to adhere to our prescribers instructions for use and not to exceed the recommended dosage. Potential side effects may include scalp irritation, dryness, and itching. It is recommended to consult with a healthcare professional if these or any other side effects occur. The carrier agent used to deliver the active ingredient to your scalp is free from the potentially harsh chemicals ethanol and propylene glycol. We opted for a highly spreadable hydrophilic solution containing mineral salts of vegetable origin (TrichoSol™). Making this an alcohol-free treatment. Base solution (TrichoSol™): Aqua, lactic Acid, polysorbate 80, lavandula officinalis water parfum phenoxyethanol, rosmarinus officinalis leaf oil, ethylhexylglycerin, BHT, juniperus communis fruit oil, juniperus virginiana wood oil, amyris balsamifera bark oil, lavandula angustifolia herb oil, melaleuca alternifolia leaf oil, eucalyptus globulus leaf oil. If you have any questions about GrowBack's Minoxidil 5%, Finasteride 0.25% and Tretinoin 0.01% Scalp Serum , please do not hesitate to contact us. Our team is here to provide the information and support you need. How Does It Work Minoxidil is a well-known vasodilator that is commonly used to treat hair loss. It works by widening blood vessels and opening potassium channels, which allows more oxygen, blood, and nutrients to reach the hair follicles. This action can stimulate hair growth and extend the growth phase of the hair cycle. Finasteride 0.25% is a type of medication known as a 5-alpha-reductase inhibitor. It works by targeting the enzyme 5-alpha-reductase, which is responsible for the conversion of testosterone to dihydrotestosterone (DHT). DHT is a hormone that has been implicated in the miniaturisation of hair follicles, leading to hair loss. By inhibiting this enzyme, finasteride effectively reduces DHT levels in the scalp, which helps to halt the progression of hair loss and in some cases, may even reverse it by allowing hair follicles to regain their normal size and function. Tretinoin, a derivative of vitamin A, is included at a 0.01% concentration. It promotes skin cell turnover and can help improve the skin's texture and tone. In the context of hair loss, tretinoin is believed to enhance the penetration of minoxidil, increasing its effectiveness. When Will I See Results? It usually takes months or years for you to lose hair, so it can take several weeks to GrowBack. 80% of our patients see results within 3-4 months. In the rare instance, that the results are not as desirable as you want, we can increase the strength or add other active ingredients based on your hair health profile. The best results will come from continued use of your recommended treatments and are seen after 4-6 months. You will need to maintain the treatment for continual growth and reduced hair shedding. Possible Side Effects Side Effects – Finasteride Sexual Dysfunction (uncommon), Breast abnormalities; skin reactions (frequency unknown), Angioedema; depression; infertility male; palpitations; testicular pain. Conception and Contraception Finasteride is excreted in semen and use of a condom is recommended if sexual partner is pregnant or likely to become pregnant. Like all medicines, your Personalised Scalp Application can cause side effects, although not everybody gets them. Personalised Scalp Applications may cause the following side effects of unknown frequency (frequency cannot be estimated from the available data): • Skin irritation may occur. If this happens stop using the product. • Unwanted non-scalp hair has occasionally been reported. Always wash your hands thoroughly after application and if you accidentally apply the solution to parts of the body other than the scalp, rinse thoroughly with plenty of water. • Scalp irritation such as local redness, itchiness, dryness, flaky skin have all been reported. This may be due to propylene glycol in the product. This is usually only a temporary effect, but if it is persistent, you should stop using this product. • Temporary hair loss may occur during the first 2 – 6 weeks of use. This is likely to be because of a change within the growth cycle and it should stop within a couple of weeks. If this hair loss continues for longer than 2 weeks, stop using the product and talk to your prescribing pharmacist. • Change in hair colour and / or texture may occur. Please be aware that this treatment may take up to 4-6 months of regular use to show noticeable results. How To Use This formulation can be used by both men and, women (with caution). Avoid if pregnant or breast feeding. If you are on any medication, please check with our clinical prescriber before using this formulation. Always perform a patch test before applying to the whole scalp. Apply a small amount of the scalp serum on your scalp and leave on for a few hours. Monitor and observe to check for any irritation, redness, itching or blistering. If there is of these reactions please contact us immediately. If no reactions have been observed then proceed to apply the scalp serum to the areas of treatment. On the first application only use half the dosage amount and leave overnight. If you haven't had any reactions then continue your treatment at full optimal dosing as instructed. To apply a solution medication, we recommend the following steps: 1. Part your hair down the middle of your head. Then, use a dropper to apply the medication along the part, from the front of your scalp to the back. Make sure you continuously, but gently squeeze out small amounts of the medication as you work your way along the part with the dropper. 2. Part your hair a second and third time to the right and left of your middle part, about 2 inches down. Continuously apply the medication along each part from the front of your scalp to the back. 3. Part your hair a fourth and fifth time just above your right and left ears. Continuously apply the medication along each part from the front of your scalp to the back. Safety Information Talk to your prescriber: • If you suffer from heart disease, including abnormal heart rhythms or rates, angina, or chest pains and / or circulation disorders. • If you are at all unsure whether your scalp is normal and healthy. • If you, or a close relative, are suffering or has suffered cancer. • If you have had any allergic reactions to any applications. • If you are pregnant, breast feeding or are planning a family. • If you are unsure of why you have been prescribed this formula. Take special care when using this product: • Keep the product away from your eyes and mouth. • Wash your hands straight after application. • Before first use, perform a patch test as explained in initial consultation. • Store product as per dispensing label instructions. • Use pipette to measure doses. One dose is equivalent to 1ml. • Do not exceed 2ml within 24 hours. Side Effects – Finasteride Sexual Dysfunction (uncommon), Breast abnormalities; skin reactions (frequency unknown), Angioedema; depression; infertility male; palpitations; testicular pain. Conception and Contraception Finasteride is excreted in semen and use of a condom is recommended if sexual partner is pregnant or likely to become pregnant Driving and using machinery Using this product is not known to affect your ability to drive or use machinery. Continued use of application • You may need to use this medicine daily for at least 4 months before you see new hair growth, this is because hair growth is a slow process. • Hair growth may be soft and downy at the start but should eventually become the same as normal hair. • Once the hair has begun to re-grow, you need to continue using this medicine daily for the growth to continue. • When you stop using the medicine, the hair that has re-grown may disappear after 3-4 months and the balding / hair loss process will continue. • If you have no improvement in your hair growth after one year of use, you should discontinue treatment. • Your prescribing pharmacist will guide you each month and will monitor your hair growth progress.

Minoxidil 5%, Melatonin 1% and 17-alpha Estradiol 0.05% Topical Scalp Serum (Alcohol Free) The active ingredients in this formulation include Minoxidil 5%, Melatonin 1% and 17-alpha Estradiol 0.05%. Minoxidil 5% is a potent vasodilator utilised in the treatment of hair loss and pattern baldness. It functions by enhancing blood circulation to the scalp, thereby stimulating hair growth. Melatonin is included for its anti-inflammatory, DHT blocking and antioxidant effects, which can help repair and rejuvenate the skin. 17-alpha Estradiol inhibits the conversion of testosterone to the metabolite dihydrotestosterone (DHT) by suppressing5AR activity. In addition, by inhibiting dehydrogenase, it reduces the conversion process of androstenedione to testosterone, resulting in a reduction in the synthesis of testosterone and DHT. Making this formulation an effective treatment for conditions such as Alopecia, Androgenic Alopecia and Menopausal Female Pattern Hair Loss. Personalised Hair Growth Treatments Ongoing Clinical Guidance and Support Medical Consultation Required Request Prescription Formula Information GrowBack's Minoxidil 5%, Melatonin 1% and 17-alpha Estradiol 0.05% Scalp Serum is a specially compounded liquid formulation designed for topical application to the scalp. This unique blend of active ingredients is dispensed in a dropper bottle for precise and controlled administration, ensuring targeted treatment for a variety of hair loss and scalp conditions. Minoxidil, a potent vasodilator, works by increasing blood flow to the scalp, thereby stimulating hair growth. Minoxidil may stimulate the growth of human hairs by prolonging anagen through these proliferative and anti-apoptotic effects on dermal papillary cells (DPCs). Minoxidil, the second active ingredient, is a well-known vasodilator that has been proven to stimulate hair growth and slow balding. It functions by widening blood vessels and opening potassium channels, which allows more oxygen, blood, and nutrients to the follicle. This results in a revitalisation of shrunken hair follicles, increasing their size, and prolonging the growth phase of the hair cycle. Melatonin, a powerful antioxidant, protects the scalp from oxidative damage that can lead to hair loss, aids in reducing inflammation, blocks dihydratestosterone (DHT) and aids in promoting healthy skin cells on the scalp. 17-alpha Estradiol inhibits the conversion of testosterone to the metabolite dihydrotestosterone (DHT) by suppressing5AR activity. In addition, by inhibiting dehydrogenase, it reduces the conversion process of androstenedione to testosterone, resulting in a reduction in the synthesis of testosterone and DHT. This powerful combination formulation is an effective treatment for a range of hair loss and scalp conditions, including male and female pattern baldness, alopecia areata, and preventative hair loss. When used as directed, this formulation is safe and effective. It is important for patients to adhere to our prescribers instructions for use and not to exceed the recommended dosage. Potential side effects may include scalp irritation, dryness, and itching. It is recommended to consult with a healthcare professional if these or any other side effects occur. The carrier agent used to deliver the active ingredient to your scalp is free from the potentially harsh chemicals ethanol and propylene glycol. We opted for a highly spreadable hydrophilic solution containing mineral salts of vegetable origin (TrichoSol™). Making this an alcohol-free treatment. Base solution (TrichoSol™): Aqua, lactic Acid, polysorbate 80, lavandula officinalis water parfum phenoxyethanol, rosmarinus officinalis leaf oil, ethylhexylglycerin, BHT, juniperus communis fruit oil, juniperus virginiana wood oil, amyris balsamifera bark oil, lavandula angustifolia herb oil, melaleuca alternifolia leaf oil, eucalyptus globulus leaf oil. If you have any questions about GrowBack's Minoxidil 5%, Melatonin 1% and 17-alpha Estradiol 0.05% Scalp Serum , please do not hesitate to contact us. Our team is here to provide the information and support you need. How Does It Work Minoxidil is a well-known vasodilator that is commonly used to treat hair loss. It works by widening blood vessels and opening potassium channels, which allows more oxygen, blood, and nutrients to reach the hair follicles. This action can stimulate hair growth and extend the growth phase of the hair cycle. Melatonin, a powerful antioxidant, protects the scalp from oxidative damage that can lead to hair loss, aids in reducing inflammation, blocks dihydratestosterone (DHT) and aids in promoting healthy skin cells on the scalp. 17-alpha Estradiol inhibits the conversion of testosterone to the metabolite dihydrotestosterone (DHT) by suppressing 5AR activity. In addition, by inhibiting dehydrogenase, it reduces the conversion process of androstenedione to testosterone, resulting in a reduction in the synthesis of testosterone and DHT. When Will I See Results? It usually takes months or years for you to lose hair, so it can take several weeks to GrowBack. 80% of our patients see results within 3-4 months. In the rare instance, that the results are not as desirable as you want, we can increase the strength or add other active ingredients based on your hair health profile. The best results will come from continued use of your recommended treatments and are seen after 4-6 months. You will need to maintain the treatment for continual growth and reduced hair shedding. Possible Side Effects Like all medicines, your Personalised Scalp Application can cause side effects, although not everybody gets them. Personalised Scalp Applications may cause the following side effects of unknown frequency (frequency cannot be estimated from the available data): • Skin irritation may occur. If this happens stop using the product. • Unwanted non-scalp hair has occasionally been reported. Always wash your hands thoroughly after application and if you accidentally apply the solution to parts of the body other than the scalp, rinse thoroughly with plenty of water. • Scalp irritation such as local redness, itchiness, dryness, flaky skin have all been reported. This may be due to propylene glycol in the product. This is usually only a temporary effect, but if it is persistent, you should stop using this product. • Temporary hair loss may occur during the first 2 – 6 weeks of use. This is likely to be because of a change within the growth cycle and it should stop within a couple of weeks. If this hair loss continues for longer than 2 weeks, stop using the product and talk to your prescribing pharmacist. • Change in hair colour and / or texture may occur. Please be aware that this treatment may take up to 4-6 months of regular use to show noticeable results. How To Use This formulation can be used by both men and women. Avoid if pregnant or breast feeding. If you are on any medication, please check with our clinical prescriber before using this formulation. Always perform a patch test before applying to the whole scalp. Apply a small amount of the scalp serum on your scalp and leave on for a few hours. Monitor and observe to check for any irritation, redness, itching or blistering. If there is of these reactions please contact us immediately. If no reactions have been observed then proceed to apply the scalp serum to the areas of treatment. On the first application only use half the dosage amount and leave overnight. If you haven't had any reactions then continue your treatment at full optimal dosing as instructed. To apply a solution medication, we recommend the following steps: 1. Part your hair down the middle of your head. Then, use a dropper to apply the medication along the part, from the front of your scalp to the back. Make sure you continuously, but gently squeeze out small amounts of the medication as you work your way along the part with the dropper. 2. Part your hair a second and third time to the right and left of your middle part, about 2 inches down. Continuously apply the medication along each part from the front of your scalp to the back. 3. Part your hair a fourth and fifth time just above your right and left ears. Continuously apply the medication along each part from the front of your scalp to the back. Safety Information Talk to your prescriber: • If you suffer from heart disease, including abnormal heart rhythms or rates, angina, or chest pains and / or circulation disorders. • If you are at all unsure whether your scalp is normal and healthy. • If you, or a close relative, are suffering or has suffered cancer. • If you have had any allergic reactions to any applications. • If you are pregnant, breast feeding or are planning a family. • If you are unsure of why you have been prescribed this formula. Take special care when using this product: • Keep the product away from your eyes and mouth. • Wash your hands straight after application. • Before first use, perform a patch test as explained in initial consultation. • Store product as per dispensing label instructions. • Use pipette to measure doses. One dose is equivalent to 1ml. • Do not exceed 2ml within 24 hours. Side Effects – Dutasteride Sexual Dysfunction (uncommon), Breast abnormalities; skin reactions (frequency unknown), Angioedema; depression; infertility male; palpitations; testicular pain. Conception and Contraception Dutasteride is excreted in semen and use of a condom is recommended if sexual partner is pregnant or likely to become pregnant Driving and using machinery Using this product is not known to affect your ability to drive or use machinery. Continued use of application • You may need to use this medicine daily for at least 4 months before you see new hair growth, this is because hair growth is a slow process. • Hair growth may be soft and downy at the start but should eventually become the same as normal hair. • Once the hair has begun to re-grow, you need to continue using this medicine daily for the growth to continue. • When you stop using the medicine, the hair that has re-grown may disappear after 3-4 months and the balding / hair loss process will continue. • If you have no improvement in your hair growth after one year of use, you should discontinue treatment. • Your prescribing pharmacist will guide you each month and will monitor your hair growth progress.

< Back The heading for the fifth case study would appear in here Gender Male Age 35 Complaint Scalp discomfort (stinging sensation, itchiness) and hair loss over the past 7 months. Evaluation The patient was presenting scalp discomfort, reported as a stinging sensation and itchiness. Systemic symptoms were not reported. A dermatological exam revealed frontoparietal alopecia, essentially irregular, with scaling and diffuse erythema. During scalp examination, scales and tonsured hair were easily removed with damp gauze. The patient had no atrophy areas and skin lesions on other parts of the body. The patient reported previous treatment with: • Clobetasol 0.05% hydroalcoholic lotion - once daily for 3 months • Ketoconazole 2.0% shampoo - 3 times per week • Previous use of betamethasone 0.05% hydroalcoholic lotion The patient had not performed previous exams (direct mycological, culture, and anatomopathological examinations). She was advised to stop using the lotion and shampoo to perform the mycological examination and fungal culture. Figure 1. Hair shaft images before treatment (baseline), and after 90 days. Assessment Chronic tinea capitis (Trichophyton tonsurans). The patient had no immunological disorders that could be responsible for the chronicity of the fungal infection and she denied similar cases in the family. Treatment As the direct mycological examination and the fungal culture were positive for Trichophyton tonsurans and the previous treatment was not successful and even aggravated the inflammation, with progressive worsening, we changed and corrected the treatment using terbinafine 250 mg/day for 6 weeks, followed by TrichoConcept™ protocol for 90 days (to accelerate hair growth). After 6 weeks of Terbinafine use, the direct mycological examination and fungal culture were repeated and the result was negative, so TrichoConcept™ protocol was started as described below: 1. TrichoOil™ - Pure, apply to the scalp and hair before washing, and leave for 10 minutes. Use 1x per week. 2. TrichoWash™ - Pure, apply to wet hair, massage the scalp for 2 minutes, and rinse. Use daily. 3. TrichoCond™ - Pure, apply to wet hair after the shampoo, massage the scalp and hair for 2 minutes, and rinse. Use daily. 4. TrichoSol™ - With minoxidil 3.0%. Apply to towel-dry hair, and massage the scalp for 2 minutes. Use daily. Results New hair growth and significant improvement in scalp inflammation were observed after 90 days of treatment with the TrichoConcept™ protocol (Figure 1 ). Subjective Results The patient reported new hair growth and increased hair density. Regulation of sebum production, a well-balanced scalp, and shinier hair shafts were also related. This perception led to greater adherence to treatment as the patient did not report side effects and discomforts. Previous Next

Minoxidil 7% and Caffeine 2% Topical Scalp Serum (Alcohol Free) The active ingredients in this formulation include Minoxidil 7% and Caffeine 2% Topical Scalp Serum (Alcohol Free). Minoxidil is a potent vasodilator utilised in the treatment of hair loss and pattern baldness. It functions by enhancing blood circulation to the scalp, thereby stimulating hair growth. Caffeine, is known for its anti-inflammatory and antioxidant properties. Caffeine stimulates blood flow and reduces inflammation. Caffeine stimulates blood flow and reduces inflammation. Caffeine, is known for its anti-inflammatory and antioxidant properties, making it an effective treatment for conditions such as Alopecia, Androgenic Alopecia, Telogen Effluvium, Trichotillomania, and Female Pattern Hair Loss. Making this formulation an effective treatment for conditions such as Alopecia, Androgenic Alopecia and Menopausal Female Pattern Hair Loss. This combination is best suited to those have have difficulty in growing hair in length, and those that have had hair loss due to a stress induced event. Personalised Hair Growth Treatments Ongoing Clinical Guidance and Support Medical Consultation Required Request Prescription Formula Information GrowBack's Minoxidil 7% and Caffeine 2% Topical Scalp Serum (Alcohol Free) Scalp Serum is a specially compounded liquid formulation designed for topical application to the scalp. This unique blend of active ingredients is dispensed in a dropper bottle for precise and controlled administration, ensuring targeted treatment for a variety of hair loss and scalp conditions. Minoxidil, a potent vasodilator, works by increasing blood flow to the scalp, thereby stimulating hair growth. Minoxidil may stimulate the growth of human hairs by prolonging anagen through these proliferative and anti-apoptotic effects on dermal papillary cells (DPCs). Minoxidil, the second active ingredient, is a well-known vasodilator that has been proven to stimulate hair growth and slow balding. It functions by widening blood vessels and opening potassium channels, which allows more oxygen, blood, and nutrients to the follicle. This results in a revitalisation of shrunken hair follicles, increasing their size, and prolonging the growth phase of the hair cycle. Caffeine, is known for its anti-inflammatory and antioxidant properties, making it an effective treatment for conditions such as Alopecia, Androgenic Alopecia, Telogen Effluvium, Trichotillomania, and Female Pattern Hair Loss. This powerful combination formulation is an effective treatment for a range of hair loss and scalp conditions, including male and female pattern baldness, alopecia areata, and preventative hair loss. When used as directed, this formulation is safe and effective. It is important for patients to adhere to our prescribers instructions for use and not to exceed the recommended dosage. Potential side effects may include scalp irritation, dryness, and itching. It is recommended to consult with a healthcare professional if these or any other side effects occur. The carrier agent used to deliver the active ingredient to your scalp is free from the potentially harsh chemicals ethanol and propylene glycol. We opted for a highly spreadable hydrophilic solution containing mineral salts of vegetable origin (TrichoSol™). Making this an alcohol-free treatment. Base solution (TrichoSol™): Aqua, lactic Acid, polysorbate 80, lavandula officinalis water parfum phenoxyethanol, rosmarinus officinalis leaf oil, ethylhexylglycerin, BHT, juniperus communis fruit oil, juniperus virginiana wood oil, amyris balsamifera bark oil, lavandula angustifolia herb oil, melaleuca alternifolia leaf oil, eucalyptus globulus leaf oil. If you have any questions about GrowBack's Minoxidil 7% and Caffeine 2% Topical Scalp Serum (Alcohol Free) Scalp Serum , please do not hesitate to contact us. Our team is here to provide the information and support you need. How Does It Work Minoxidil is a well-known vasodilator that is commonly used to treat hair loss. It works by widening blood vessels and opening potassium channels, which allows more oxygen, blood, and nutrients to reach the hair follicles. This action can stimulate hair growth and extend the growth phase of the hair cycle. Caffeine, is known for its anti-inflammatory and antioxidant properties, making it an effective treatment for conditions such as Alopecia, Androgenic Alopecia, Telogen Effluvium, Trichotillomania, and Female Pattern Hair Loss. When Will I See Results? It usually takes months or years for you to lose hair, so it can take several weeks to GrowBack. 80% of our patients see results within 3-4 months. In the rare instance, that the results are not as desirable as you want, we can increase the strength or add other active ingredients based on your hair health profile. The best results will come from continued use of your recommended treatments and are seen after 4-6 months. You will need to maintain the treatment for continual growth and reduced hair shedding. Possible Side Effects Like all medicines, your Personalised Scalp Application can cause side effects, although not everybody gets them. Personalised Scalp Applications may cause the following side effects of unknown frequency (frequency cannot be estimated from the available data): • Skin irritation may occur. If this happens stop using the product. • Unwanted non-scalp hair has occasionally been reported. Always wash your hands thoroughly after application and if you accidentally apply the solution to parts of the body other than the scalp, rinse thoroughly with plenty of water. • Scalp irritation such as local redness, itchiness, dryness, flaky skin have all been reported. This may be due to propylene glycol in the product. This is usually only a temporary effect, but if it is persistent, you should stop using this product. • Temporary hair loss may occur during the first 2 – 6 weeks of use. This is likely to be because of a change within the growth cycle and it should stop within a couple of weeks. If this hair loss continues for longer than 2 weeks, stop using the product and talk to your prescribing pharmacist. • Change in hair colour and / or texture may occur. Please be aware that this treatment may take up to 4-6 months of regular use to show noticeable results. How To Use This formulation can be used by both men and women. Avoid if pregnant or breast feeding. If you are on any medication, please check with our clinical prescriber before using this formulation. Always perform a patch test before applying to the whole scalp. Apply a small amount of the scalp serum on your scalp and leave on for a few hours. Monitor and observe to check for any irritation, redness, itching or blistering. If there is of these reactions please contact us immediately. If no reactions have been observed then proceed to apply the scalp serum to the areas of treatment. On the first application only use half the dosage amount and leave overnight. If you haven't had any reactions then continue your treatment at full optimal dosing as instructed. To apply a solution medication, we recommend the following steps: 1. Part your hair down the middle of your head. Then, use a dropper to apply the medication along the part, from the front of your scalp to the back. Make sure you continuously, but gently squeeze out small amounts of the medication as you work your way along the part with the dropper. 2. Part your hair a second and third time to the right and left of your middle part, about 2 inches down. Continuously apply the medication along each part from the front of your scalp to the back. 3. Part your hair a fourth and fifth time just above your right and left ears. Continuously apply the medication along each part from the front of your scalp to the back. Safety Information Talk to your prescriber: • If you suffer from heart disease, including abnormal heart rhythms or rates, angina, or chest pains and / or circulation disorders. • If you are at all unsure whether your scalp is normal and healthy. • If you, or a close relative, are suffering or has suffered cancer. • If you have had any allergic reactions to any applications. • If you are pregnant, breast feeding or are planning a family. • If you are unsure of why you have been prescribed this formula. Take special care when using this product: • Keep the product away from your eyes and mouth. • Wash your hands straight after application. • Before first use, perform a patch test as explained in initial consultation. • Store product as per dispensing label instructions. • Use pipette to measure doses. One dose is equivalent to 1ml. • Do not exceed 2ml within 24 hours. Side Effects – 17-alpha Estradiol - Generally the side effects are mild and localised at application site. These side effects below are rare and minimal due to use being topical. Sexual Dysfunction (uncommon), Breast abnormalities; skin reactions (frequency unknown), changes in menstrual cycles in women and potential effects on hormone-sensitive conditions. Driving and using machinery Using this product is not known to affect your ability to drive or use machinery. Continued use of application • You may need to use this medicine daily for at least 4 months before you see new hair growth, this is because hair growth is a slow process. • Hair growth may be soft and downy at the start but should eventually become the same as normal hair. • Once the hair has begun to re-grow, you need to continue using this medicine daily for the growth to continue. • When you stop using the medicine, the hair that has re-grown may disappear after 3-4 months and the balding / hair loss process will continue. • If you have no improvement in your hair growth after one year of use, you should discontinue treatment. • Your prescribing pharmacist will guide you each month and will monitor your hair growth progress.

We are hear to help you Grow Back Hair with personalised hair loss treatments First name* Last name* Email* Mobile Phone Number* Our prescriber will use this number to contact you for any medical information required. Please select one choice* I am a GrowBack Patient I am not a GrowBack Patient Please note if you are not a registered GrowBack Patient that you understand by completing a purchase does not guarantee supply of treatment; the final decision to prescribe lies with the prescriber with your best interests, health and appropriateness in mind. There will be a charge for the review and consultation of £40 if you are not suitable for this treatment. An alternative treatement will be suggested by our prescriber. Formulation* Minoxidil 7% and Dutasteride 0.25% Topical Scalp Serum (Alcohol Free) 60ml £ 119 Postage £ 6.99 Any information you'd like our prescriber to know? Submit

Latanoprost 0.008% and Minoxidil 5% Topical Scalp Serum (Alcohol Free) The active ingredients in this formulation include Latanoprost 0.008% and Minoxidil 5%. Latanoprost stimulates the anagen phase of the hair growth cycle. The anagen phase is the growth phase. Minoxidil 5% is a potent vasodilator utilised in the treatment of hair loss and pattern baldness. It functions by enhancing blood circulation to the scalp, thereby stimulating hair growth. Making this formulation an effective treatment for conditions such as Alopecia, Androgenic Alopecia and Menopausal Female Pattern Hair Loss. This combination is best suited to those have have difficulty in growing hair in length, and those that have had hair loss due to a stress induced event. Personalised Hair Growth Treatments Ongoing Clinical Guidance and Support Medical Consultation Required Request Prescription Formula Information GrowBack's Latanoprost 0.008% and Minoxidil 5% Scalp Serum is a specially compounded liquid formulation designed for topical application to the scalp. This unique blend of active ingredients is dispensed in a dropper bottle for precise and controlled administration, ensuring targeted treatment for a variety of hair loss and scalp conditions. Latanoprost stimulates the anagen phase of the hair growth cycle. The anagen phase is the growth phase. Latanoprost helps more hair convert from tiny, thin vellus (think peach fuzz) hair into robust terminal hair that is longer and thicker. Increases hair density and stimulates healthy hair follicle activity Minoxidil, a potent vasodilator, works by increasing blood flow to the scalp, thereby stimulating hair growth. Minoxidil may stimulate the growth of human hairs by prolonging anagen through these proliferative and anti-apoptotic effects on dermal papillary cells (DPCs). Minoxidil, the second active ingredient, is a well-known vasodilator that has been proven to stimulate hair growth and slow balding. It functions by widening blood vessels and opening potassium channels, which allows more oxygen, blood, and nutrients to the follicle. This results in a revitalisation of shrunken hair follicles, increasing their size, and prolonging the growth phase of the hair cycle. This powerful combination formulation is an effective treatment for a range of hair loss and scalp conditions, including male and female pattern baldness, alopecia areata, and preventative hair loss. When used as directed, this formulation is safe and effective. It is important for patients to adhere to our prescribers instructions for use and not to exceed the recommended dosage. Potential side effects may include scalp irritation, dryness, and itching. It is recommended to consult with a healthcare professional if these or any other side effects occur. The carrier agent used to deliver the active ingredient to your scalp is free from the potentially harsh chemicals ethanol and propylene glycol. We opted for a highly spreadable hydrophilic solution containing mineral salts of vegetable origin (TrichoSol™). Making this an alcohol-free treatment. Base solution (TrichoSol™): Aqua, lactic Acid, polysorbate 80, lavandula officinalis water parfum phenoxyethanol, rosmarinus officinalis leaf oil, ethylhexylglycerin, BHT, juniperus communis fruit oil, juniperus virginiana wood oil, amyris balsamifera bark oil, lavandula angustifolia herb oil, melaleuca alternifolia leaf oil, eucalyptus globulus leaf oil. If you have any questions about GrowBack's Latanoprost 0.008% and Minoxidil 5% Scalp Serum , please do not hesitate to contact us. Our team is here to provide the information and support you need. How Does It Work Latanoprost stimulates the anagen phase of the hair growth cycle. The anagen phase is the growth phase. Latanoprost helps more hair convert from tiny, thin vellus (think peach fuzz) hair into robust terminal hair that is longer and thicker. Increases hair density and stimulates healthy hair follicle activity. Minoxidil, a potent vasodilator, works by increasing blood flow to the scalp, thereby stimulating hair growth. Minoxidil may stimulate the growth of human hairs by prolonging anagen through these proliferative and anti-apoptotic effects on dermal papillary cells (DPCs). Minoxidil, the second active ingredient, is a well-known vasodilator that has been proven to stimulate hair growth and slow balding. It functions by widening blood vessels and opening potassium channels, which allows more oxygen, blood, and nutrients to the follicle. This results in a revitalisation of shrunken hair follicles, increasing their size, and prolonging the growth phase of the hair cycle. When Will I See Results? It usually takes months or years for you to lose hair, so it can take several weeks to GrowBack. 80% of our patients see results within 3-4 months. In the rare instance, that the results are not as desirable as you want, we can increase the strength or add other active ingredients based on your hair health profile. The best results will come from continued use of your recommended treatments and are seen after 4-6 months. You will need to maintain the treatment for continual growth and reduced hair shedding. Possible Side Effects Like all medicines, your Personalised Scalp Application can cause side effects, although not everybody gets them. Personalised Scalp Applications may cause the following side effects of unknown frequency (frequency cannot be estimated from the available data): • Skin irritation may occur. If this happens stop using the product. • Unwanted non-scalp hair has occasionally been reported. Always wash your hands thoroughly after application and if you accidentally apply the solution to parts of the body other than the scalp, rinse thoroughly with plenty of water. • Scalp irritation such as local redness, itchiness, dryness, flaky skin have all been reported. This may be due to propylene glycol in the product. This is usually only a temporary effect, but if it is persistent, you should stop using this product. • Temporary hair loss may occur during the first 2 – 6 weeks of use. This is likely to be because of a change within the growth cycle and it should stop within a couple of weeks. If this hair loss continues for longer than 2 weeks, stop using the product and talk to your prescribing pharmacist. • Change in hair colour and / or texture may occur. Please be aware that this treatment may take up to 4-6 months of regular use to show noticeable results. How To Use This formulation can be used by both men and women. Avoid if pregnant or breast feeding. If you are on any medication, please check with our clinical prescriber before using this formulation. Always perform a patch test before applying to the whole scalp. Apply a small amount of the scalp serum on your scalp and leave on for a few hours. Monitor and observe to check for any irritation, redness, itching or blistering. If there is of these reactions please contact us immediately. If no reactions have been observed then proceed to apply the scalp serum to the areas of treatment. On the first application only use half the dosage amount and leave overnight. If you haven't had any reactions then continue your treatment at full optimal dosing as instructed. To apply a solution medication, we recommend the following steps: 1. Part your hair down the middle of your head. Then, use a dropper to apply the medication along the part, from the front of your scalp to the back. Make sure you continuously, but gently squeeze out small amounts of the medication as you work your way along the part with the dropper. 2. Part your hair a second and third time to the right and left of your middle part, about 2 inches down. Continuously apply the medication along each part from the front of your scalp to the back. 3. Part your hair a fourth and fifth time just above your right and left ears. Continuously apply the medication along each part from the front of your scalp to the back. Safety Information Talk to your prescriber: • If you suffer from heart disease, including abnormal heart rhythms or rates, angina, or chest pains and / or circulation disorders. • If you are at all unsure whether your scalp is normal and healthy. • If you, or a close relative, are suffering or has suffered cancer. • If you have had any allergic reactions to any applications. • If you are pregnant, breast feeding or are planning a family. • If you are unsure of why you have been prescribed this formula. Take special care when using this product: • Keep the product away from your eyes and mouth. • Wash your hands straight after application. • Before first use, perform a patch test as explained in initial consultation. • Store product as per dispensing label instructions. • Use pipette to measure doses. One dose is equivalent to 1ml. • Do not exceed 2ml within 24 hours. Driving and using machinery Using this product is not known to affect your ability to drive or use machinery. Continued use of application • You may need to use this medicine daily for at least 4 months before you see new hair growth, this is because hair growth is a slow process. • Hair growth may be soft and downy at the start but should eventually become the same as normal hair. • Once the hair has begun to re-grow, you need to continue using this medicine daily for the growth to continue. • When you stop using the medicine, the hair that has re-grown may disappear after 3-4 months and the balding / hair loss process will continue. • If you have no improvement in your hair growth after one year of use, you should discontinue treatment. • Your prescribing pharmacist will guide you each month and will monitor your hair growth progress.